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Beyond nine lives

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<h2 style="text-align:left">Cats age too quickly.</h2>
<p class="large" style="text-align:left">By the time most people notice their cat is getting older, it’s already too late to intervene. Age-related decline has set in: arthritis, cognitive changes, loss of mobility, and a drop in quality of life. This isn’t just heartbreaking: it’s unnecessary.</p>
<p class="large" style="text-align:left">At The Cat Health Company, we believe aging is a biological process that can be slowed, paused, or even reversed.</p>
<p class="large" style="text-align:left"><strong>We’re building the first longevity medicines for cats.</strong></p>

Through computational modeling, machine learning algorithms, and in silico prediction, we are designing and optimising evidence-based medicines that address the molecular mechanisms of aging in cats.

In silico strategies for feline longevity

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<h2>Why cats?</h2>
<p>Cats are family. Yet while human medicine has made huge strides, our cats are still underserved. Most medications focus on symptoms, not the root causes of aging.</p>
<p>We’re changing that.</p>
<p>By treating the biology of aging itself, we aim to delay disease onset, extend healthy lifespan and improve quality of life in senior cats.</p>

Bengal cat gives a paw to its owner. High five.

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We believe cats deserve more, and that solving aging in cats will help us solve it everywhere.

Cats are a unique model for human aging

<p>They share our homes, lifestyles, and many diseases of aging.</p>

Shared environment

<p style="text-align: justify;">Their shorter lifespans allow us to see effects faster than in human trials.</p>

Faster discovery

<p style="text-align: left;">Research in cats may help pave the way for broader applications, in both veterinary and human medicine.</p>

Broader applications

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Team members

Our world-class team of scientists, clinicians and pharma industry experts are leading the mission to go beyond just nine lives.

About us

<p style="text-align: justify;">Co-founder &amp; CEO - Doctorate in Molecular and Cellular Medicine from the University of Oxford, previously led projects at Genevia Technologies and biotech startups</p>

Alex Voda, DPhil

<p style="text-align: justify;">Co-founder &amp; COO - University of Manchester almnus, previously senior scientist and project lead in pharma, worked at Biorelate, Labcorp, Charles River Labs in drug discovery roles</p>

Alex Bacita, BSc

<p>Clinical - Senior doctor in veterinary medicine, focused on geriatric pathologies in companion cats, practitioner with experience in clinical trials</p>

Ana Cruceanu, DVM

<p style="text-align: justify;">Scientist - Previously worked on molecular genetics at The University of Manchester and in cellular senescence with Verdin lab at The Buck Institute for Aging</p>

Cristina Alexandru, PhD

<p style="text-align: justify;">Counsel &amp; external legal coordinator - Previously assisting on legal matters and interactions with regulatory agencies for NGOs and parliament senators </p>

Mihai Tanase, Esq

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We develop advanced therapeutic programs using our in-house SOTA ML models and our laboratory validations, some of which have reached clinical stages.

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Recent blog posts

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<h2>The Intriguing Connection Between Cats and Human Aging</h2>
<p>Have you ever wondered if our feline companions could hold the key to unlocking the mysteries of human aging? While it may seem far-fetched at first glance, scientists are increasingly interested in how studying cats might offer insights into the complex process of aging in humans. Cats, with their unique biological and genetic makeup, could provide valuable clues in understanding how we age and how we might improve quality of life as we grow older.</p>

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<h3>The Biological Similarities Between Cats and Humans</h3>
<p>Cats and humans share a surprising number of biological similarities. Both species have similar organs and systems that function in comparable ways. For instance, the structure of a cat’s brain is remarkably similar to that of a human, featuring analogous regions for processing emotions and memories. These similarities suggest that studying cats could help us gain a deeper understanding of the aging process in humans.</p>

<p>Moreover, cats experience many of the same age-related conditions as humans do. Arthritis, kidney disease, and cognitive decline are common ailments found in older cats, mirroring the health challenges faced by aging humans. By researching how these diseases manifest and progress in cats, scientists hope to uncover new treatments and preventive measures that could benefit both species.</p>

<h3>Genetic Insights from Feline Studies</h3>
<p>Another promising avenue of research lies in the genetic makeup of cats. Scientists have already identified certain genes in cats that are linked to aging and longevity. By examining these genes, researchers aim to discover how they influence the aging process and whether similar genes play a role in human aging. This genetic research could potentially lead to breakthroughs in extending healthy human lifespan.</p>

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<p>Some studies focus on telomeres, the protective caps at the ends of chromosomes that shorten as cells divide. Shortened telomeres are associated with aging and age-related diseases. Interestingly, cats appear to maintain their telomere length for a longer period compared to other animals. Understanding how cats achieve this could reveal strategies to preserve telomere length in humans, potentially slowing down the aging process.</p>

<h3>Behavioral Observations and Aging</h3>
<p>Cats not only provide physical and genetic insights but also offer behavioral clues about aging. Observing changes in a cat's behavior as they age can help researchers identify early signs of cognitive decline, which might mirror similar patterns in humans. Studying these behavioral shifts in cats can guide the development of cognitive assessments and interventions for aging humans.</p>

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<p>Furthermore, the social interactions of cats with humans and other animals can provide valuable information about emotional well-being in older age. Understanding how companionship affects the mental health of aging cats might shed light on the importance of social connections for elderly individuals.</p>

<h3>The Future of Aging Research</h3>
<p>The potential for cats to contribute to our understanding of human aging is vast and largely untapped. As research progresses, it will be crucial for scientists to continue exploring these parallels between feline and human aging. Collaborative efforts between veterinarians, geneticists, and gerontologists will likely yield exciting advancements in this field.</p>

<p>In conclusion, while it might seem unusual to look to our feline friends for answers about our own aging process, the potential benefits are significant. By studying cats, we can gain insights into biological mechanisms, genetic factors, and behavioral patterns that influence aging. These findings could ultimately lead to improved health outcomes and a better quality of life for both humans and their beloved pets.</p>

How Cats Could Help Us Understand Human Aging

senior  woman holding a cat smiling indoors

<h2>Understanding Healthspan versus Lifespan</h2><p>When it comes to our feline companions, many cat owners focus primarily on lifespan, hoping to keep their furry friends around for as long as possible. However, it's equally important to consider <strong>healthspan</strong>—the period during which a cat is not just alive, but also healthy and active. Prioritizing healthspan ensures that your cat enjoys a better quality of life throughout their years.</p><p>While advances in veterinary medicine have certainly helped extend a cat's lifespan, focusing on healthspan involves a more holistic approach. This means not only addressing medical needs but also considering diet, exercise, mental stimulation, and emotional well-being.</p><figure id="figure-8284u2bbm5mekhxeh2"><img id="8284u2bbm5mekhxeh2" src="/id/1287491166/photo/very-active-3-months-kitten-climbing-curtains.jpg?b=1&amp;s=2048x2048&amp;w=0&amp;k=20&amp;c=4Fhtm-z_OdY7j-ppkRY6Kvtv4wHoGGA6lkIMFof8wDs=" alt="Very active 3 months kitten climbing curtains." title="Very active 3 months kitten climbing curtains." class="object-cover bg-gray-100 rounded-2xl md:rounded-3xl lg:rounded-4xl" style="aspect-ratio: 16/9; object-position: center center;" data-corners="default" data-aspect="16:9" data-caption="" data-positionx="null" data-positiony="null" data-fullwidth="false" data-mce-src="/id/1287491166/photo/very-active-3-months-kitten-climbing-curtains.jpg?b=1&amp;s=2048x2048&amp;w=0&amp;k=20&amp;c=4Fhtm-z_OdY7j-ppkRY6Kvtv4wHoGGA6lkIMFof8wDs=" data-mce-style="aspect-ratio: 16/9; object-position: center center;"></figure><h2>The Role of Nutrition in Healthspan</h2><p>Proper nutrition is a cornerstone of extending your cat's healthspan. A balanced diet supports their immune system, maintains a healthy weight, and ensures they have the energy to play and explore. Consider the following nutritional tips:</p><ul><li>Choose high-quality food that meets your cat's specific age and health needs.</li><li>Incorporate a mix of wet and dry food to promote hydration.</li><li>Avoid overfeeding to prevent obesity, which can lead to a host of health problems.</li></ul><p>It's advisable to consult with your veterinarian to tailor a diet plan specific to your cat's needs. Foods rich in omega-3 fatty acids can also promote a healthy coat and skin, while antioxidants support overall health.</p><h2>Importance of Regular Exercise</h2><p>Exercise is just as vital for cats as it is for humans. Regular physical activity helps maintain muscle mass, supports cardiovascular health, and prevents obesity. Engaging your cat in daily play sessions can significantly enhance their healthspan.</p><p>Use interactive toys or laser pointers to encourage your cat to move. Climbing structures like cat trees can also provide both exercise and mental stimulation. Remember, a physically active cat is generally a happier and healthier one.</p><h2>Mental Stimulation and Emotional Care</h2><p>Mental stimulation is another essential component of extending your cat's healthspan. Boredom can lead to depression and behavioral issues in cats. To keep your cat mentally sharp, consider activities such as:</p><ol><li>Puzzle feeders that challenge them to work for their food.</li><li>Interactive toys that mimic the hunt-and-catch experience.</li><li>Regular changes in their environment to provide new stimuli.</li></ol><p>Additionally, emotional care is crucial. Cats are sensitive creatures that thrive on affection and routine. Providing a stable home environment with plenty of love and attention can make a significant difference in their overall well-being.</p><h2>Regular Veterinary Check-Ups</h2><p>Routine veterinary visits are essential for monitoring your cat's health and catching potential issues early. Regular check-ups allow for vaccinations, dental care, and the detection of early signs of illness. Early intervention often leads to better outcomes and can extend both lifespan and healthspan.</p><h2>Conclusion: A Holistic Approach</h2><p>Extending your cat's healthspan requires more than just medical care; it involves a comprehensive approach that encompasses diet, exercise, mental stimulation, and emotional well-being. By focusing on these areas, you can ensure that your feline friend not only lives longer but enjoys each day to the fullest.</p><p>Remember, every cat is unique, so tailoring these strategies to suit your pet’s individual needs will help them lead a healthier, happier life.</p>

Extending Cat Healthspan: Beyond Longevity to Quality of Life

Young Beautiful Female Holding Pet at Doctor's Appointment at a Modern Veterinary Clinic. Red Maine Coon Stands on Examination Table While Female Vet Inspects the Cat

<h2>Understanding the Importance of Feline Safety in Clinical Trials</h2><p>Clinical trials are a crucial aspect of veterinary medicine, allowing researchers to develop new treatments and therapies that improve the health and well-being of cats. However, ensuring the safety and care of feline participants is of utmost importance throughout this process. By prioritizing their welfare, we can achieve accurate results while maintaining ethical standards.</p><figure id="figure-lbzg3rtaxlmekhr4q3"><img id="lbzg3rtaxlmekhr4q3" src="/id/2161573244/photo/shot-of-cat-lying-on-the-floor-and-sleep-at-living-room-with-home-surveillance-camera.jpg?b=1&amp;s=2048x2048&amp;w=0&amp;k=20&amp;c=sDom2oFOFg-VUWYTt4M5FCPutOpbc5I8W-ZdCgyTl2I=" alt="Shot of cat lying on the floor and sleep at living room with home surveillance camera." title="Shot of cat lying on the floor and sleep at living room with home surveillance camera." class="object-cover bg-gray-100 rounded-2xl md:rounded-3xl lg:rounded-4xl" style="aspect-ratio: 16/9; object-position: center center;" data-corners="default" data-aspect="16:9" data-caption="" data-positionx="null" data-positiony="null" data-fullwidth="false" data-mce-src="/id/2161573244/photo/shot-of-cat-lying-on-the-floor-and-sleep-at-living-room-with-home-surveillance-camera.jpg?b=1&amp;s=2048x2048&amp;w=0&amp;k=20&amp;c=sDom2oFOFg-VUWYTt4M5FCPutOpbc5I8W-ZdCgyTl2I=" data-mce-style="aspect-ratio: 16/9; object-position: center center;"></figure><h3>Pre-Trial Safety Measures</h3><p>Before any clinical trial begins, a comprehensive set of pre-trial safety measures is implemented. This includes thorough veterinary examinations to assess the overall health and suitability of each cat for participation. Only cats meeting specific health criteria are selected to ensure they can safely undergo the trial procedures.</p><p>Additionally, all trial protocols undergo rigorous review by ethical committees to ensure they adhere to established animal welfare guidelines. This step is crucial in making sure that the trials are conducted responsibly and with the least amount of distress to the animals involved.</p><h3>During the Trial: Monitoring and Care</h3><p>Once the trial is underway, continuous monitoring of the feline participants is essential. Veterinary professionals and trained staff are present at all times to observe any changes in the cats' behavior or health. This allows for immediate intervention if any adverse effects are detected, ensuring that the well-being of the cats remains a top priority.</p><p>The environment in which the trials take place is also designed to minimize stress and provide comfort. Cats are kept in spaces that mimic their natural habitats, with plenty of enrichment activities and resting areas to promote a sense of security and contentment.</p><h3>Post-Trial Assessments</h3><p>After the completion of a clinical trial, detailed post-trial assessments are conducted on each feline participant. These assessments include physical examinations and behavioral evaluations to ensure that no long-term adverse effects have occurred as a result of the trial.</p><p>Furthermore, all findings from the trial are meticulously documented and reviewed. This data is not only crucial for advancing veterinary medicine but also serves as a testament to the commitment to feline safety and care throughout the research process.</p><h3>The Role of Informed Consent</h3><p>Informed consent is a critical component of ethical clinical trials involving animals. Owners of feline participants are provided with comprehensive information about the trial's purpose, procedures, and potential risks. Their voluntary agreement ensures transparency and fosters trust between researchers and pet owners.</p><p>By involving pet owners in the decision-making process, we not only uphold ethical standards but also empower them to make informed choices about their pets' involvement in clinical research.</p><h2>Conclusion: Commitment to Ethical Research</h2><p>The commitment to ensuring feline safety and care in clinical trials is unwavering. By implementing robust safety measures, providing continuous monitoring, and maintaining transparency with pet owners, we can advance veterinary research responsibly. This approach not only benefits the feline participants but also contributes to the development of safer and more effective treatments for all cats.</p><p>As we continue to explore new frontiers in veterinary medicine, our dedication to ethical research practices remains at the forefront, ensuring that every step taken is in the best interest of our feline companions.</p>

Inside Our Clinical Trials: Ensuring Feline Safety and Care

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<h3>Press, investors, pet owners, veterinarians and potential scientific collaborators can contact us through this form</h3>

Beyond nine lives

Cats age too quickly.

In silico strategies for feline longevity

Why cats?

Cats are a unique model for human aging

About us

Pipeline

Mews

Oversubscribed Pre-Seed

Purring Into The Future

Recent blog posts

How Cats Could Help Us Understand Human Aging

Extending Cat Healthspan: Beyond Longevity to Quality of ...

Inside Our Clinical Trials: Ensuring Feline Safety and Care

Press, investors, pet owners, veterinarians and potential scientific collaborators can contact us through this form